Česko-slovenská pediatrie, 2024 (vol. 79), Suppl.4

Recommendations of the Working group for paediatric gastroenterology hepatology and nutrition of the

Jan Melek, Simona Bělohlávková, Vendula Látalová, Jakub Pecl, Markéta Štanclová, Ondřej Hradský, Petr Jabandžiev, Eva Karásková, Jan Schwarz, Martin Zimen, Vanda Mečiarová, Kateřina Kamarádová, Petra Rozsívalová, Jiří Bronský

Čes-slov Pediat 2024, 79(90):5-28 | DOI: 10.55095/CSPediatrie2024/061  

EoE (Eosinophilic Esophagitis) is a chronic, progressive, immune-mediated disease characterized by an eosinophil-predominant infiltration of the esophageal mucosa (≥15 eosinophils per high-power field in at least one biopsy sample) in the absence of other causes of esophageal eosinophilia. Significant ri sk factors for the development of EoE include male gender, atopy, history of esophageal atresia, and a positive family history. In the personal medical history of children with EoE, conditions such as asthma, allergic rhinitis, atopic dermatitis, and food allergies are often present. Symptoms in infants and younger children tend to be nonspecific...