Čes-slov Pediat 2024, 79(88):9-12 | DOI: 10.55095/CSPediatrie2024/027
Meningococcal infections in childhoodComprehensive Report
- Klinika infekčních nemocí, Fakultní nemocnice Bulovka, Praha
Meningococcal infections count among the most dangerous infectious conditions that may affect humans regardless of their age. Anyway, the age groups at highest risk are children up to age 4 years, and adolescents. Adolescents are not only at risk of being infected but also to become source of infection for the contacts when serving as carriers of Neisseria meningitidis infection.
The incidence of meningoccal infections in the Czech Republic is not high. In 2023 there were 17 cases of invasive meningococcal diseases confirmed.(1) The spectrum of clinical expression is broad. The illnesses may be
divided into noninvasive and invasive. In invasive, their morality rate reaches 10% and severe sequelae 20%.(2) The only protection that can prevent illness is vaccination. Thera are now
vaccines available against serotypes A, C, W, Y, B.
Keywords: meningococcal infections, clinical course, therapy, contact protection
Accepted: May 7, 2024; Published: August 1, 2024 Show citation
References
- Informační systém infekčních nemocí. Dostupné na: https://www.uzis.czWHO. Factsheet No. 141. 2015. Dostupné na: http://www.who.int/mediacentre/factsheets/fs141/en/
- CDC. Pinkbook: Meningococcal Disease. Dostupné na: https://www.cdc.gov/vaccines/pubs/pinkbook/mening.html
- Van Deuren M, et al. Clinical Microbiology Reviews. 2000: 144-166.
Go to original source...
- Sabra A, Benger J. Meningococcal disease in children: a clinical review. Turk J Pediatr 2011; 53: 477-488.
- Národní referenční laboratoř pro meningokokové nákazy, Státní zdravotní ústav v Praze. Kumulativní surveillance dat IMO za období 2013-2022.
- Brouwer MC, Read RC, Van de Beek D. Host genetics and outcome in meningococcal disease: a systematic review and meta-analysis. Lancet Infect Dis 2010; 10: 262-274.
Go to original source...
Go to PubMed...
- Křížová P. Med praxi 2020; 17(5): 317-320.
- Sadarangani, et al. Clin Infect Dis 2015; 60: e27-35.
Go to original source...
Go to PubMed...
- Gammelgaard LK, Colding H, Hartzen SH, et al. Meningococcal disease and future drug targets, CNS Neurol Disord Drug Targets 2011; 10: 140-145.
Go to original source...
Go to PubMed...
- WHO. Factsheet. Dostupné na: https://www.who.int/news-room/fact-sheets/detail/meningitis
- Hamborsky, et al. Epidemiology and prevention of vaccine-preventable diseases. 14th ed. 2015: 331-46.
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