Čes-slov Pediat 2024, 79(4):226-232 | DOI: 10.55095/CSPediatrie2024/037

Malabsorption syndromes

Martina Ambrozová^{1, 2}, Matěj Hrunka^{1, 2}, Petr Jabandžiev^{1, 2, 3}

¹ Pediatrická klinika, Fakultní nemocnice Brno

² Lékařská fakulta, Masarykova univerzita, Brno

³ RECETOX, Přírodovědecká fakulta, Masarykova univerzita, Brno

Malabsorption syndromes represent a large group of diseases characterized by impaired intraluminal digestion or nutrient absorption and typically manifest as

diarrhea, steatorrhea, bloating and/or failure to thrive. Some diseases may be accompanied by specific symptoms such as oedema, digital clubbing and perianal exanthema. This article aims to classify malabsorption syndromes based on recent findings and summarize their etiology, etiopathogenesis and clinical manifestation. We review current diagnostic and therapeutic approaches.

In accordance with the section in which the text will be published, frequent nosological entities will be discussed. Rarer diseases (such as malabsorption due to graft versus host disease) will be mentioned briefly, we direct readers to relevant and detailed sources.

Keywords: malabsorption syndrome, chronic cholestasis, exocrine pancreatic insufficiency, celiac disease, protein-losing enteropathy, lactase deficiency, short bowel syndrome, small intestinal bacterial overgrowth.

Accepted: May 31, 2024; Published: August 1, 2024  Show citation