JOURNAL OF THE CZECH PEDIATRIC SOCIETY AND THE SLOVAK PEDIATRIC SOCIETY

Čes-slov Pediat 2025, 80(1):20-25 | DOI: 10.55095/CSPediatrie2025/003

Diagnostic methods in hypoxic-ischemic encephalopathy of newborns

Eva Štěpánová1, 2, 3, Hana Wiedermannová4, 5, David Krahulík6, Pavla Hanzlíková7, 8
1 Oddělení dětské neurologie, Fakultní nemocnice Ostrava
2 Katedra neurověd, Ostravská univerzita, Ostrava
3 Neurologická klinika, Lékařská fakulta, Univerzita Palackého a Fakultní nemocnice Olomouc
4 Oddělení neonatologie, Fakultní nemocnice Ostrava
5 Katedra dětského lékařství, Ostravská univerzita, Ostrava
6 Neurochirurgická klinika, Lékařská fakulta, Univerzita Palackého a Fakultní nemocnice Olomouc
7 Ústav radiodiagnostický, Fakultní nemocnice Ostrava
8 Ústav zobrazovacích metod, Ostravská univerzita, Ostrava

Hypoxic-ischemic encephalopathy (HIE) is the most serious cause of neonatal morbidity and mortality; it involves damage to the brain of a full-term newborn; in premature infants, it occurs in the form of periventricular leukomalacia. The incidence of HIE is approximately 1-3 per 1000 live births worldwide. The most severe forms of HIE, according to some sources, represent up to a 60

% risk of death, therefore rapid and timely diagnosis, especially of moderate to severe forms, early transport to a perinatological center and indication of therapeutic hypothermia can mitigate and predict the consequences of asphyxiation damage. This communication aims to create an overview of current diagnostic option for HIE, especially imaging methods focusing on magnetic resonance imaging.

Keywords: therapeutic hypothermia, examination methods, T1 relaxometry

Accepted: December 4, 2024; Published: February 1, 2025  Show citation

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Štěpánová E, Wiedermannová H, Krahulík D, Hanzlíková P. Diagnostic methods in hypoxic-ischemic encephalopathy of newborns. Ces-slov Pediat. 2025;80(1):20-25. doi: 10.55095/CSPediatrie2025/003.
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