Čes-slov Pediat 2022, 77(1):27-33 | DOI: 10.55095/CSPediatrie2022/004

Perinatal outcome of SARS-CoV-2 infection in pregnancyOriginal Papers

Peter Korček^{1, 2}, Hana Urbancová³, Šárka Hadravská^{4, 5}, Zbyněk Straňák^{1, 2}

¹ Ústav pro péči o matku a dítě - neonatologie, Praha

² 3. lékařská fakulta Univerzity Karlovy

³ Ústav pro péči o matku a dítě - klinická patologie, Praha

⁴ Bioptická laboratoř s.r.o., Plzeň

⁵ Šiklův ústav patologie, Fakultní nemocnice Plzeň

SARS-CoV-2 placentitis is a rare and serious complication of COVID-19 disease in pregnancy. The coronavirus placental infection may lead to maternal and fetal vascular malperfusion (pregnancy itself is a prothrombotic state), fetal demise, intrauterine hypoxia, fetal growth restriction, or preterm birth with the accompanying neonatal morbidity. In case of transplacental transmission of SARS-CoV-2,

newborns can also suffer from early-onset viral pneumonia. Consequently, comprehensive epidemiology control sho

uld be implemented during pregnancy (frequent testing, contact tracing, vaccination). Furthermore, anticoagulation prophylaxis (low-molecular-weight heparin) and thorough fetal surveillance may be employed in COVID-positive pregnancies, especially in high-risk cases with preexisting placental insufficiency.

Keywords: SARS-CoV-2, covid-19, placenta, perinatology, perinatal morbidity

Published: January 21, 2022  Show citation