JOURNAL OF THE CZECH PEDIATRIC SOCIETY AND THE SLOVAK PEDIATRIC SOCIETY

Čes-slov Pediat 2024, 79(2):89-92 | DOI: 10.55095/CSPediatrie2024/012

Vitamin/hormone D in pediatric rheumatology - minireview and summary for clinical practice

Kateřina Bouchalová1, Tereza Flögelová2, Zuzana Pytelová1
1 Dětská klinika, Lékařská fakulta, Univerzita Palackého v Olomouci a FN Olomouc
2 Lékařská fakulta, Univerzita Palackého v Olomouci

Vitamin/hormone D plays an important role in pediatric rheumatology. Besides its antiinfectious effects, antiinflammatory function is currently studied. Randomised double-blind placebo-controlled study in adolescents with systemic lupus erythematosus (SLE) revealed, that vitamin D supplementation led to decrease in disease activity and to reduction of fatigue. In nonsystemic juvenile idiopathic arthritis (JIA), vitamin D is a biomarker, which in combination with other clinical and laboratory markers plays a role in prediction of outcome (inactive disease). Study on periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome (PFAPA) detected association of low vitamin D levels with longer episode duration and shorter time between episodes. This paper review an information on vitamin D role in pediatric rheumatolog y and highlights possibilities of vitamin D supplementation in routine clinical practice.

Keywords: vitamin D, 25-hydroxy-vitamin D, cholecalciferol, systemic lupus erythematosus, juvenile idiopathic arthritic, periodic fever syndrome PFAPA, infection, therapy, prevention

Received: February 4, 2024; Revised: February 4, 2024; Accepted: February 6, 2024; Published: April 1, 2024  Show citation

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Bouchalová K, Flögelová T, Pytelová Z. Vitamin/hormone D in pediatric rheumatology - minireview and summary for clinical practice. Ces-slov Pediat. 2024;79(2):89-92. doi: 10.55095/CSPediatrie2024/012.
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