JOURNAL OF THE CZECH PEDIATRIC SOCIETY AND THE SLOVAK PEDIATRIC SOCIETY

Čes-slov Pediat 2023, 78(4):210-214 | DOI: 10.55095/CSPediatrie2023/037

The use of contrast-enhanced ultrasound in diagnosis of liver tumors in newbornsCase Histories

Marek Pršo1, Zuzana Michnová1, Marek Kozár2, Linda Pršová1, Lýdia Zúbriková1, Zuzana Havlíčeková1, Daniela Kosorínová1, Michaela Murgašová1, Kristián Pršo3, Peter Bánovčin1
1 Klinika detí a dorastu, Univerzita Komenského v Bratislave, Jesseniova lekárska fakulta v Martine, Univerzitná nemocnica Martin
2 Neonatologická klinika, Univerzita Komenského v Bratislave, Jesseniova lekárska fakulta v Martine, Univerzitná nemocnica Martin
3 Ústav farmakológie, Univerzita Komenského v Bratislave, Jesseniova lekárska fakulta v Martine

Aim: Contrast-enhanced ultrasound (CEUS) is a novel diagnostic method that enables dynamic imaging of tissues in real time with recording characteristic pattern of bearing contrast agent in liver lesion. The aim of the authors is to point out the importance of this imaging modality in the differential diagnosis of liver tumors in newborns through the presentation of two case reports.

Methodology: After intravenous application of microbubble contrast agent with exclusively intravascular distribution the si gnal intensity is recorded in the individual phases of the examination in liver lesion and its surroundings. During the arterial phase the vascularization of the lesion is evaluated, in the portal and late phase is possible to specify the dignity of the liver lesion more precisely.

Results: Two newborns with liver tumors underwent CEUS examination with the aim of closer characterization of the le sion. Based on the CEUS in these newborns were diagnosed hemangioma and hepatoblastoma. We did not observe any adverse effects related to the intravenous administration of the contrast agent.

Conclusion: According to our expiriences so far is CEUS a suitable diagnostic method in differential diagnosis of liver tumors also at patients of neonatal age. Realization and interpretation of results reguire trained medical staff.

Keywords: CEUS, contrast-enhanced ultrasound, diagnostics, liver tumors, neonatology

Published: July 1, 2023  Show citation

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Pršo M, Michnová Z, Kozár M, Pršová L, Zúbriková L, Havlíčeková Z, et al.. The use of contrast-enhanced ultrasound in diagnosis of liver tumors in newborns. Ces-slov Pediat. 2023;78(4):210-214. doi: 10.55095/CSPediatrie2023/037.
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