Čes-slov Pediat 2023, 78(6):295-297 | DOI: 10.55095/CSPediatrie2023/049
Brief resolved unexplained event (BRUE)
BRUE is a new term created in 2016 by the American Academy of Pediatrics, replacing previously used term ALTE (Apparently Life Threatening Event). The change occurred due to the inaccuracy of the original
definition of ALTE, which is difficult to apply in the clinical practice and research. BRUE is defined as a brief, spontaneously resolved, unexplained medical event that may occur in a child under 1 year of age and this event meets the diagnostic criteria for the condition. Symptoms include irregular breathing, skin discoloration, muscle tone changes, or disturbances in consciousness. BRUE is a
diagnosis by exclusion. The aim of this article is to define the concept of BRUE and its criteria, determine the patient's level of risk, and provide recommendations for further investigation management.
Keywords: BRUE, ALTE, low-risk BRUE, high-risk BRUE
Accepted: October 23, 2023; Published: December 11, 2023 Show citation
References
- Tieder JS, Bonkowsky JL, Etzel RA, et al. Clinical practice guideline: Brief resolved unexplained events (formerly apparent life-threatening events) and evaluation of lower risk infants: executive summary. Pediatrics 2016; 137(5): e20160591.
Go to original source... 
Go to PubMed... - Monti MC, Borrelli P, Nosetti L, et al. Incidence of apparent life-threatening events and post-neonatal risk factors. Acta Paediatr 2017; 106: 204. Go to original source... Go to PubMed...
- Klásková E, David J. Algoritmus pro rozpoznání vážně nemocného dítěte. Čes-slov Pediat 2022; 77(5): 284-286. Go to original source...
- Merritt JL 2nd, Quinonez RA, Bonkowsky JL, et al. A framework for evaluation of the higher-risk infant after a brief resolved unexplained events. Pediatrics 2019; 144(2):e20184101 Go to original source... Go to PubMed...
- Colombo M, Katz ES, Bosco A, et al. Brief resolved unexplained events: Retrospective validation of diagnostic criteria and risk stratification. Pediatr Pulmonol 2019; 54: 61. Go to original source... Go to PubMed...
This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (CC BY 4.0), which permits use, distribution, and reproduction in any medium, provided the original publication is properly cited. No use, distribution or reproduction is permitted which does not comply with these terms.